文档介绍：
环境响应型突释微囊研究新进展#
巨晓洁,谢锐,汪伟,褚良银*
(四川大学化学工程学院,成都 610065)
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摘要:环境响应型智能微载体材料可以响应温度、pH 值、磁场、化学物质等环境刺激的微
小变化,实现物质的自律式控制释放,在药物送达、酶和细胞固定化、分离纯化等领域显
示出突出的优越性,具有广泛应用前景。本文综述了环境响应型“突释”控释微囊材料方
面的研究新进展,着重介绍了温度响应型、pH 响应型、离子识别响应型“突释模式”控释
微囊的制备与性能方面的研究新成果。目前,环境响应型智能微载体材料仍多处于基础研
究阶段,还需要进一步系统深入研究和开发完善。
关键词:生物化工;环境响应型;突释;智能微囊;功能材料
中图分类号:TB34
Recent Progress in Environmental-Responsive
Microcapsules for Controlled Burst-Release
JU Xiaojie, XIE Rui, WANG Wei, CHU Liangyin
(School of Chemical Engineering, Sichuan University, Chengdu 610065)
Abstract: Environmental stimuli-responsive smart microcarrier materials, which can realize the
self-regulated controlled-release in response to the change of temperature, pH, ic field and
special chemicals in external environment, exhibit excellent superiorities in various fields, such as drug
delivery, immobilization of enzyme and cells, separation and purification of chemicals. In this paper,
the progress of the development of environmental stimuli-responsive smart microcapsules for
controlled burst-release is introduced. Especially, the thermo-responsive, pH-responsive and
ion-recognition smart microcapsules for burst-release are introduced and reviewed systematically. At
present, environmental stimuli-responsive smart microcarrier materials are still in the basic research
stage and need further intensive study