C 反应蛋白在焊工尘肺患者血清中含量分析.doc

文档介绍：C反应蛋白在焊工尘肺患者血清中含量分析
张强1 雷清1 胡小明2 张光凤2
九江市第六人民医院:检验科1,办公室2
九江市2010年第二批社会发展类指导性科研计划项目课题【九科字(2010)55号026】
摘要:目的探讨C反应蛋白(C-reactive protein,CRP)与焊工尘肺进展的相关性,意在对焊工尘肺的诊断和治疗有指导意义方法选取经职业病诊断机构诊断的患者一,二期患者60名,及健康对照60名抽全血生化检查,重点观察CRP的含量,将结果进行统计分析。结果 1, 60例尘肺病患者CRP的含量明显高于对照组,差异有统计学意义(P<) 2,焊工尘肺一期CRP 与二期患者的CRP无明显差异(P>) 结论本研究结果显示血清CRP含量与焊工尘肺的疾病密切相关
关键词焊工尘肺 C反应蛋白
Relationship between C-reactive Protein and Pneumoconiosis in Welders Patients
Zhang Qiang1, Lei Qing1, Hu Xiaoming2, Zhang Guangfeng2
(The Sixth hospital of Jiujiang City, clinical laboratory department1, hospital office2)
Abstract Objective To investigate the relation between C-reactive protein and pneumoconiosis in welders, guiding the diagnosis and therapy for pneumoconiosis.
Methods 60 pneumoconiosis patients (I and II period), diagnosed by an anization, and 20 healthy people were randomly selected. C-reactive protein (CRP) was tested and analyzed. Results CRP were significant higher in pneumoconiosis patients than it was in healthy people (P<); But there was no significance of CRP in I period patients and II period patients. Conclusions CRP is closely related to pneumoconiosis in welders.
Key words Welder; Pneumoconiosis; C-reactive protein
焊工尘肺是电焊工人长期大量吸入电焊烟尘所致的尘肺。电焊烟尘是由于高温使焊药、焊条芯和被焊接材料溶化蒸发,逸散在空气中氧化冷凝而形成的颗粒极细的气溶胶,吸入肺泡中长时间引起肺组织弥漫性纤维化变化,形成肺部网状结节影的病症。C反应蛋白最早发现其在急性大叶性肺炎患者血清中,能在钙离子存在时与肺炎球菌C多糖起沉淀反应而得名[1],,C反应蛋白