文档介绍：老年脑梗死患者高同型半胱氨酸血症与颈动脉硬化的关系
作者:贺刚锐王建平白宏英王金兰刘春岭
【摘要】目的研究老年性脑梗死患者颈动脉硬化(CAA)与高同型半胱氨酸血症(HHcy)的关系,为脑梗死的防治提供新手段。方法对105例60岁以上脑梗死患者行颈动脉彩色多普勒超声检查,以颈动脉彩超检查结果分为颈动脉中重度狭窄组、颈动脉轻度狭窄组和颈动脉内膜正常组。另选34例健康体检者为对照组。应用微粒子酶联免疫分析法测定空腹血浆同型半胱氨酸(Hcy),并对部分服用叶酸、维生素B12患者进行随访。结果颈动脉中,/L,有非常显著性差异(P&lt;)。颈动脉轻度狭窄组与颈动脉内膜正常组Hcy水平相比有显著性差异(P&lt;), ,,具有显著性差异(P&lt;)。结论血Hcy水平与脑梗死患者颈动脉硬化程度密切相关,对HHcy患者进行干预是一种值得研究的脑梗死防治手段。
【关键词】脑梗死;高同型半胱氨酸血症;颈动脉硬化;危险因素
【Abstract】 Objective To study the relationship between serum homocysteine(Hcy) levels and carotid artery arteriosclerosis (CAA) in old cerebral infarction patients, and to provide new treatment for cerebral infarction . Methods One hundred and five patients older than 60 years with cerebral infarction were examined by color Doppler ultrasonography to detect CAA patients were divided into three groups based on the severity of s
tenosis of CAA: the moderatesevere stenosis group,the slight stenosis group,and normal results of serum Hcy levels in different groups The Hcy level of moderatesevere group was ,while the Hcy level of normal group was ,and the Hcy level of the slight stenosis group was was statistically significant difference of Hcy level between the moderatesev