文档介绍：MRI动态增强在鉴别前列腺增生及前列腺癌中的价值
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作者:王华, 段青, 威晋, 游精航, 孙斌
【摘要】 T磁共振动态增强扫描在前列腺增生与前列腺癌中的鉴别诊断价值。VIBE序列动态增强扫描,分析所得出的信号-时间曲线信号变化及走行趋势,并进行统计学分析。结果增强峰值时间前列腺癌早于前列腺增生,强化程度与强化率前列腺癌也高于前列腺增生()。前列腺增生信号时间曲线类型以上升型为主,而前列腺癌以流出型为主()。结论。
【关键词】磁共振成像; 图像增强; 前列腺肿瘤; 前列腺增生
ABSTRACT: Objective To assess the role of dynamic contrastenhanced ic resonance imaging (DCEMRI) at Tesla in the distinguishing prostate cancer (PC) from benign prostatic hyperplasia(BPH). Methods Thirty patients with prostate cancer and 32 patients with benign prostatic hyperplasia underwent conventional MRI and DCE
MRI using 3D VIBE sequences at Tesla. The DCEMRI signal intensity and the characteristics of signal intensitytime curve were analysed emphatically and the statistical analysis was performed. Results On the basis of the enhancement parameters of SIT curve, the peak time of Pca was earlier than that of BPH, and the enhancement degree and enhancement rate of Pca were higher than those of BPH (P0. 05). The SIT curve signal intensity of prostate cancer featured mainly as washout type while that of BPH appeared as steady enhancement type. Conclusion Dynamic contrastenhanced ic resonance imaging plays an important role in the differential diagnosis of benign prostate hyperplasia and prostate cancer.

KEY WORDS: ic resonance imaging; image enhancement; prostatic hyperplasia

前列腺疾病严重威胁着老年男性的健康,而良恶性结节的鉴别在前列腺疾病的诊断及治疗中至关重要,直接关系治疗方案的选择及病人预后。MRI具有良好的软组织分辨率,目前公认为诊断前列腺疾病的主要影像学检查方法。传统T2WI在前列腺癌的定位、诊断、分期起过重要作用,但临床应用中发现其局限性:不能诊断中央带的癌结节,另外诊断特异性低,因外周带低信号结节既可来源于癌结节,又可来源于增生性结节及炎性结节等。为了提高MRI的诊断价值,前列腺的功能性成像
DWI、动态增强、MRS及PWI已成为研究热点[1],其中动态增强MRI经过后处理能够得出反映前列腺组织微血管特性的参数,这些参数与前列腺肿瘤血管增生的标志物相关。因此,这些信息有助于鉴别良恶性前列腺组织,包括前列腺癌及前列腺增生[2]。 MR完成, MR在临床应用日渐普及,其信噪比、 MR,更适于前列腺功能成像, MR的前列腺动态成像研究在国内报道不多[3]。 MR动态增强特征,为鉴别诊断提供依据