文档介绍：PCI对冠心病患者血清hs-CRP、IL-6、ox-LDL的影响
(作者:___________单位: ___________邮编: ___________)
【摘要】目的:观察PCI对冠心病患者血IL-6、hs-CRP、ox-LDL的影响,探讨IL-6、hs-CRP、ox-LDL与冠脉病变程度的相关性。方法:对94例冠心病患者行冠状动脉造影(SCAG),按SCAG结果分为PCI组67例和对照组27例,两组均于术前及术后4小时取肘静脉血,测定血清hs-CRP、IL-6及ox-LDL水平。结果:与术前比较,PCI组术后血清hs-CRP水平显著增高(),IL-6、ox-LDL水平差异无统计学意义();与对照组比较,PCI组术前、术后血清hs-CRP、IL-6、ox-LDL水平差异均有统计学意义()。多支及双支病变组术前和术后血清hs-CRP水平显著高于单支病变组();多支病变组术前和术后IL-6水平显著性高于双支和单支病变组();三组间ox-LDL水平差异无统计学意义()。弥漫病变组和长病变组血清hs-CRP、IL-6水平明显高于局限病变组,差异有统计学意义();血清ox-LDL水平各组间比较,差异无统计学意义()。结论:炎症因子与ox-LDL对CHD的诊断、危险性预测具有临床价值。CHD患者血清IL-6、hs-CRP水平与冠脉病变程度存在相关性。
【关键词】冠心病PCIIL-6hs-CRPox-LDL
AbstractObjective:To observe the effect of percutaneous coronary internvention(PCI) on the serum l
evels of hs-CRP,IL-6 and ox-LDL in patients with coronary heart disease(CHD) and to analyze the relationship between their levels and the severity of CHD. Methods:Selective coronary angiography was performed in 94 CHD images showed that CHD patients with one-vessel,two-vessel,and multi-vessel stenosis and showed long,diffuse,and local patients were divided into PCI group (67 patients) and control group (27 patients) by different angiographic samples were harvested in 4 hours after treatment and serum hs-CRP,IL-6 and ox-LDL levels were to those before treatment,hs-CRP was sig