文档介绍：沐舒坦治疗吸入性损伤的临床研究
陈新辉沈光裕周金武陈建设
摘要目的研究沐舒坦注射液联合抗炎、机械通气、吸痰及雾化吸入治疗吸入性损伤的临床疗效。方法将30例患者随机分为治疗组16例和对照组14例,对比分析两组临床疗效、肺水肿发生率、肺部感染率及拔管时间。结果与对照组比较,沐舒坦治疗组能够明显提高临床疗效,降低肺水肿发生率和肺部感染率,缩短拔管时间。结论沐舒坦注射液能明显改善吸入性损伤后呼吸道症状,减轻肺功能的损伤,综合临床疗效显著,值得临床推广使用。
关键词:吸入性损伤,盐酸氨溴索
Abstract Objective To research the clinical effect for inhalation injury of ambroxol injection bination with anti-inflammatory, mechanical ventilation, suction and aerosol inhalation. Methods 30 patients were randomly divided into treatment group(16) and control group(14). pare clinical effect, the incidence of pulmonary edema, the incidence of pulmonary infection, and extubation time of two groups. pared with the control group, treatment group with ambroxol could improve clinical effect significantly, reduce the incidence of pulmonary edema and pulmonary infection and shorten extubation time. Conclusion Ambroxol injection could improve respiratory symptoms after inhalation injury significantly and reduce injury of lung. With integrated clinical effect is significant, it would be worth of use in clinical widely.
Key words: inhalation injury, ambroxol
吸入性损伤指热力或烟雾引起呼吸道以及肺实质的损伤,烧伤常合并吸入性损伤。近年来致伤环境的改变,吸入性发病率大为上升。随着对烧伤治疗措施逐渐完善,休克和感染死亡率明显下降,而吸入性损伤已成为当前烧伤的主要死亡原因。在行机械通气治疗的基础上给予药物治疗,对进一步降低病死率有一定价值[1]。
1 资料和方法
临床资料 2008年1月—2010年7月烧伤科收治的吸入性损伤患者30例,依据黎鳌等的吸入性损伤临床分度标准,诊断分度为中度,均行预防性气管切开,随机分为治疗组(加用沐舒坦注射液,16例)和对照组(14例),2组的烧伤面积、深度、吸入性损伤程度及患者年