文档介绍：普瑞巴林对带状疱疹后遗神经痛神经阻滞效果的影响
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李钧,钟泰迪,戴尧鑫,张华(,杭州 310009;,杭州 310016)
摘要:目的观察普瑞巴林对带状疱疹后遗神经痛神经阻滞效果的影响。方法将 40 例患者随机分为对照组(A 组)和普
瑞巴林组(B 组), 两组患者均行神经阻滞, B组加服普瑞巴林。对比观察两组患者用药前后 VAS 评分、睡眠质量评分(QS)
和不良反应。结果与治疗前比较,两组治疗后第 2 周~第 10 周,VA S 和 QS 显著下降(P<)。普瑞巴林组治疗后疼
痛 VAS 评分和睡眠质量评分均显著低于对照组(P<)。两组不良反应的发生率没有区别。结论普瑞巴林对带状疱疹
后遗神经痛的神经阻滞效果具有明显的增强作用。
关键词:普瑞巴林;神经阻滞;带状疱疹后遗神经痛
中图分类号: 文献标志码:B 文章编号:1007-7693(2012)06-0564-03
Effect of Pregabalin on Nerve Block during the Treatment of Postherpetic Neuralgia
LI Jun1, ZHONG Taidi2, DAI Yaoxing1, ZHANG Hua1( of Anesthesiology, Hangzhou Third People’s
Hospital, Hangzhou 310009, China; of Anesthesiology, Sir Run Run Show Hospital, School of Medicine, Zhejiang
University, Hangzhou 310016, China)
ABSTRACT: OBJECTIVE To observe the effect of pregabalin on nerve block during the treatment of postherpetic neuralgia.
METHODS All of 40 postherpetic neuralgia patients were divided randomly into two groups, the control group(A) and
gabapentin group(B). All patients were performed with nerve block, and the patients in group B received oral gabapentin. Visual
analog scale (VAS) and sleep quality score (QS) were evaluated and adverse reactions were recorded. RESULTS VAS and QS
in two groups decreased significantly after treatment, but VAS and QS of group B decre