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2010全国生物材料大会论文集之 (1).pdf

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2010全国生物材料大会论文集之 (1).pdf

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文档介绍:A cellular automaton model for the transmission
dynamics of schistosomiasis

Yun Liu, Kai Chu, Xiaoli Xu, Haiwei Wu* Cheng Wan
Department of Pathogen Biology Department of Public Service Management
Nanjing Medical University Nanjing Medical University
Nanjing, China Nanjing, China

Abstract—In this paper, a new stochastic model based on cellular conceptual model into a numerical setting is usually technically
automata is established to simulate the occurrence and simple and straight-forward. Hence, CA models have been
development of Schistosoma japonicum (S. japonicum) infection developed to simulate many biological systems.
in an endemic population. We included the process of the
pathogen invasion from exposure to worm development and till In this paper, a stochastic model based on CA(we name it
worm death when the infection is cleared in the model. We as SjCA) is established to simulate the transmission dynamics
further utilized the model to predict the prevalence as the of schistosomasis japonica in the endemic area. The SjCA
es of the selected chemotherapy carried out in Jiahu model is used to mimic each individual’s state and effects of
village. Comparing model predicted prevalence and intensities the selected chemotherapy carried out in Jiahu village. And the
with the observed parameters, it is anticipated that our cellular es of shi