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2010全国生物材料大会论文集之 (114).pdf

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2010全国生物材料大会论文集之 (114).pdf

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2010全国生物材料大会论文集之 (114).pdf

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文档介绍:Factors affecting Synonymous codon usage bias in
the gC gene of duck plague virus

Fu-xiao Shen, An-chun Cheng, Ming-shu Wang, Hai-Bin Ya’an, Sichuan, China
Huang, Chuan-feng Li, De-kang Zhu
Avian Disease Research Center, College of Veterinary An-chun Cheng,Xiao-yue Chen
Medicine of Sichuan Agricultural University, Epizootic Diseases Institute of Sichuan Agricultural
Ya’an, Sichuan, China University, Sichuan Agricultural University,
Ya’an, Sichuan, China
An-chun Cheng, Ming-shu Wang, De-kang Zhu,Ren-yong Jia E-mail:******@vip.
Key Laboratory of Animal Disease and Human Health of mshuwang@
Sichuan Province,


Abstract—The aim was to identify the factors affecting interaction[10], are accounting for the biased usage of
synonymous codon usage bias in the newly identified Duck Plague synonymous codons. In viruses, many literatures are recorded
Virus (DPV) gC gene, and parative analysis of the codon about the extent and origin of the synonymous codon bias.
usage bias in the gC-like genes of the 28 herpesviruses was Most retroviruses also exhibited a profound discrimination
performed by using CAI, CHIPS and CUSP program of EMBOSS. against the CpG dinucleotide sequence and the genome
The results showed that position, mutational bias bination characteristics strongly influences the codon
translation selection were the major determi