文档介绍:小儿细菌性痢疾临床特点及病原学分析
诸宏伟孙琦沈怀云彭万胜王磊
蚌埠医学院第一附属医院儿科
e-mail:zhuhongwei51136@ tel:**********
【摘要】目的了解我院近3年小儿急性细菌性痢疾的临床特点、致病菌群分布以及耐药情况。为临床合理使用抗生素提供依据。方法对2010年1月-2012年12月收住我院儿科的44例急性细菌性痢疾患儿为研究对象,对患儿的一般资料、症状、血常规、生化常规以及病原菌的分型以及耐药性情况的临床特点及药敏结果进行回顾性分析。结果小儿细菌性痢疾多流行于5-11月,以1-6岁患儿高发。病例多以普通型为主,偶有中毒型。脓血便已不是细菌性痢疾的典型表现。血液学检测白细胞增高,中性粒细胞,C反应蛋白明显增高。福氏志贺菌氏主要流行菌群。志贺菌属对头孢唑啉、氨苄青霉素几乎全部耐药,对喹诺酮类以及氨基糖苷类以及头孢曲松的耐药率也较高,对哌拉西林他唑巴坦、头孢派酮舒巴坦则全部敏感。结论:小儿细菌性痢疾临床表现亦趋于不典型和多样化,尽早做大便培养以明确。在治疗上应当首选含有β-内酰胺酶抑制剂的复方制剂。
【关键词】细菌性痢疾儿童病原学药物敏感试验
Clinical features and etiological analysis of bacillary dysentery in children
ZHU Hongwei,SUN Qi,SHEN Huaiyun,PEN Wansheng,WANG of Pediatrics,The First Hospital Affiliated to Bengbu Medical College, Bengbu,Anhui233004,China
[Abstract] Objective To investigate the clinical features of bacillary dysentery in children and its pathogen distribution and drug resistance,and to provide evidence for clinical use of A retrospective analysis was conducted in children patient with bacillary dysentery from January 2010 to December data of age,symptoms,blood test,pathogen type and its drug risistance were analyzed. Results Most cases occurred from May to prevalence was higher in children from 1 to 6 years old. Most cases belonged mon type .Toxic type is few. pus and blood stool were not the tipical count of white blood cell,neut