突发性耳聋临床诊治分析.doc

文档介绍：突发性耳聋临床诊治分析
作者:燕志强余少卿邵晓莉洪锦科高盛宏张俊周锦川
【摘要】目的探讨全身应用糖皮质激素、高压氧治疗、治疗时机选择以及发病时耳聋程度对突发性耳聋预后的影响。方法资料完整的110例(113耳)患者按不同处理方式以及听力下降程度进行回顾性对比分析,观察不同治疗方法、发病时听力改变与预后的关系。结果全身应用糖皮质激素、高压氧辅助治疗均能显著提高疗效(P<,P<),高压氧治疗还可以提高痊愈率(P<);耳聋程度影响治疗效果,程度重者有效率低,预后相对较差(P<);而早期治疗可以显著提高治疗效果以及痊愈率(P<, P<)。结论突发性耳聋患者发病后尽早开始包括地塞米松在内的药物治疗并辅助高压氧进行综合治疗有助于提高疗效和痊愈率。
【关键词】听觉丧失,突发性;感音神经性;治疗;预后
Abstract: Objective To study the factors related to the therapeutic effect and prognosis of sudden sensorineural hearing loss, including the use of systemic glucocorticosteroid and hyperbaric oxygen treatment,the timing of treatment and the degree of deafness. Methods The 110 patients (113 ears) plete clinical records were studied retrospectively. Results Both systemic glucocorticosteroid and hyperbaric oxygen adjuvant to the conventional medical therapy, enhanced the rate of effectiveness (P<,P<), with especially the hyperbaric oxygen even having elevated the rate of cure (P<)
. Degree of deafness was found related to the therapeutic efficacy, the heavier hearing loss, the lower effectiveness and worse prognosis(P<). Early treatment (<14 days after onset) would favor the rates of effectiveness and cure(P<, P<). Conclusion Early drug treatment plus glucocorticosteroid and hyperbaric oxygen adjuvants would add the rates of effectiveness and cure in patients with sudden sensorineur