文档介绍：CA 153和CEA联合检测对乳腺癌术后监测的意义
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【摘要】目的观察CA 153和CEA联合检测在乳腺癌术后监测中的价值。方法120例乳腺癌术后患者,空腹取静脉血,分别采用免疫放射分析法(IRMA)和放射免疫分析法(RIA)测定CA 153和CEA。结果①乳腺癌术后无复发转移100例,其中CA 153增高4例、CEA增高3例,%、%。复发转移20例,其中CA 153增高15例、CEA增高11例,%、%。CA 153和CEA两者均异常,在无复发转移组为0,复发转移组6例,%,联检两者之一阳性14例,%,联检与单独检测CA 153比较无显著性差异(P>)。②复发或转移乳腺癌患者CA 153和CEA水平显著高于无复发或无转移乳腺癌患者(P<)。结论CA 153和CEA的检测可作为乳腺癌术后随访的重要指标,对预测复发转移具有重要意义。
【关键词】细胞膜糖蛋白CA 153 癌胚抗原乳腺癌
The Monitoring Significance of Serum Concentrations CA 15
3 and CEA in the Postoperative Patients with Breast Cancer
【Abstract】ObjectiveTo investigate the significance bined detection of CA 153 and CEA in the postoperative patients with breast cancer. MethodsThe concentrations of CA 153 and CEA were respectively detected by IRMA and RIA in blood. Results① The levels of CA 153 in 4 cases and CEA in 3 cases were increased in the 100 postoperative breast cancer patients without recurrence and metastasis,and the positive rate is % and % respectively. In the 20 cases with recurrence and metastasis, 15 patients were measured with higher CA 153 and 11 patients with higher CEA,which the sensitivity is % and % positive patients were detected by either of the methods,which the sensitivity is %. Combined detection had no significant pared with C