文档介绍：门冬胰岛素联合甘精胰岛素治疗糖尿病的临床疗效观察[摘耍]目的探讨门冬胰岛素联合廿精胰岛素治疗糖尿病的临床疗效。方法将60例2型糖尿病(T2DM)患者按照治疗方式分为对照组与观察组各30例,对照组采用人胰岛索注射液治疗,观察组采用门冬胰岛素联合廿精胰岛素治疗。比较两组治疗前后血糖水平、胰岛B细胞功能改善情况、胰岛素用量及血糖波动情况、治疗前后患者生活质量评分变化情况。结果①两组治疗后血糖指标(FBG、2hPBG及HbAlc)水平均显著低于治疗前(P〈0・05),且观察组治疗后上述指标水平也均显著小于对照组(P<);②两组治疗后胰岛B细胞功能指标(FINS、2hINS、AI30/AG30及HOMAP)水平均显著大于治疗前(卩〈),且观察组治疗后上述指标水平也均显著大于对照组治疗后(P〈0・05);③观察组治疗后胰岛素用量及血糖波动值均显著小于对照组(卩〈)。结论门冬胰岛素联合甘精胰岛素治疗糖尿病的临床疗效显著,可有效改善患者的血糖及胰岛0细胞功能,应在临床上对该方案进行推广。[关键词]2型糖尿病(T2DM);门冬胰岛素;甘精胰岛素;临床疗效[中图分类号][文献标识码]B[文章编号]1673-9701(2015)15-0073-03[Abstract](T2DM)ordingtotreatmentwererandomlydividedintothecontrolgroupandtheobservationgroup,andthecontrolgroupwasgivenhumaninsulininjectiontherapy,binedwithglargine・paredbeforeandaftertreatment,isletPcellfunctiontoimprovethesituation,theamountofinsulin且ndbloodsugarfluctuations,①Aftertreatment,glycemicindex(FBG,2hPBGandHbAlc)levelsweresignificantlylowerthanbeforetreatment(P<),andtheabovetargetlevelsoftheobservationgroupaftertreatmentwerealsosignificantlylowerthanthoseinthecontrolgroup(P<);②Aftertreatment,characteri/且tionofislet[3cellfunctionindex(FINS,2hINS,A130/AG30andHOMAP)weresignificantlyhigherthanbeforetreatinent(P〈〈),andtheobservationgroupaftertreatmentabovetarget1evelswerealsosignificantlyhigherthanthoseinthecontrolgrou