男性冠心病患者血清载脂蛋白AI与胰岛素及C－肽的关系.doc

文档介绍：临床医学论文-男性冠心病患者血清载脂蛋白AI与胰岛素及C-肽的关系
【关键词】  冠心病;载脂蛋白AI;胰岛素;C-肽
[摘要] 目的:研究冠心病(CHD)男性患者血清载脂蛋白AI(apo AI)与胰岛素(Ins)及C肽(CP)的关系。方法:征集95例男性非糖尿病年龄在60岁下的冠心病患者和92例冠心病先证者,61例非心脏病患者,分别采集血样检测高密度脂蛋白胆固醇(HDLC),apo AI,胰岛素及C肽,葡萄糖等。所有患者的年龄、体重指数和吸烟习惯的差异不具有显著性意义。结果:高血糖(OR ,95% CI ~),胰岛素(OR ,95% CI ~),CP(,95%CI ~)和低HDLC(OR ,95%CI ~)或apo AI(OR ,95% CI ~)等都与冠心病强相关。结论:联合检测apo AI,Ins,CP等将有助于非糖尿病患者冠心病危险性的预测作用。
[关键词] 冠心病;载脂蛋白AI;胰岛素;C-肽
Correlationship Between Serum Apolipoprotein AI,Insulin and Cpeptide in Patients with Coronary Heart Diseases
Abstract:Objective To study the correlation of serum apolipoprotein AI,insulin and Cpeptide in male patients with coronary heart diseases(CHD).Methods 95male nondiabetic patients were blod samples of all subjects were collected,and high density lipoprotein cholesterol (HDLC),apolipoprotein AI,insulin,Cpeptide,glucose,ect were subjects were matched by age,body mass index,and smoking High serum levels of glucose(OR ,95% CI ~),insulin(OR ,95% CI ~),and Cpeptide(OR ,95% CI ~)as well as low serum levels of HDL cholesterol (OR ,95%CI ~)or apolipoprotein AI(OR ,95%CI ~)had significant association with bined measurement of apolipoprotein AI,insulin and Cpeptide may improve identification of nondiabetic patients at inc