文档介绍：2017-CSPPT 一级高血压卒中预防
ORIGINALRESEARCH
plicatedGrade1Hypertension
XianhuiQin,MD,PhD;*YoubaoLi,MD;*NinglingSun,MD;MingliHe,MD;GenfuTang,MD;DeluYin,MD;JiGuangWang,MD;MinLiang,MD;BinyanWang,MD;YongHuo,MD;XinXu,MD;XipingXu,MD,PhD;FanFanHou,MD,PhD
Background-
—Weaimedtotesttheimpactofachievedbloodpressure(BP)on?rststrokeamongpatientswithgrade1hypertensionandwithoutcardiovasculardiseasesintheChinaStrokePrimaryPreventionTrial.
MethodsandResults-—:(1)theproportionofvisitsinwhichBPwasreducedto<140/90mmHg,and(2)thetime-averagedsystolicBP(SBP)
%,theriskofstrokedecreasedwiththeincreaseoftheproportionofstudyvisitswithBP<140/90mmHg(forper5%increase;hazardratio,[95%CI,–]).paredwithpatientswithtime-averagedSBP≥140ordiastolicBP≥90mmHg,theriskofstrokewaslowerinpatientswithtime-averagedSBPof120to<140mmHg(%%;hazardratio,[95%CI,–])ordiastolicBP<90mmHg(%%;hazardratio,[95%CI,–]).Thebene?cialresultswereconsistentacrossage(<60versus≥60years),sex,baselineSBP(<150versus150to<160mmHg),studytreatmentgroups(enalaprilorenalapril-folicacid),andhypertensionsubtypes(isolatedsystolichyperten