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广泛性焦虑症的认知研究
孟焱张红星李战文
[摘要] 目的探讨广泛性焦虑症(generalized anxiety disorder ,GAD)的认知障碍的特点。方法对89例广泛性焦虑症患者采用事件相关电位P300及韦氏智力量表与对照组比较。结果焦虑组P300电位成分中N2、P3潜伏期延长, P3波幅降低,与对照组比较存在显著性差异(t=-,-,,P均<0. 01);焦虑组与对照组比较在领悟、数字广度、词汇、编码、填图各分测验有显著差异(t=,,,,,P均<0. 01); N2潜伏期延长与领悟、填图显著相关, P3潜伏期延长与领悟、数字广度、编码显著相关, P3波幅与领悟显著相关。结论提示广泛性焦虑症存在有广泛的认知障碍。
【关键词】广泛性焦虑症;认知障碍;韦氏智力量表;诱发电位
Cognitive function in patients with generalized anxiety disorder Meng Yan,Zhang Hong-xing,Li Zhan-wen. The Clinical Depatrment of Second Affiliated Hospital of Xinxiang Medical University, Xinxiang He-Nan 453002,China
【Abstract】 Objective To investigate characteristic of the cognitive disorder in GAD. Methods 89 patients with GAD and 78 normal persons were measured by P300 and Wechsler Intelligence Scale. Results The latencies of N2、P3 were prolonged significantly and amplitude of P3 was reduced significantly in pared with the control group(t=-,-,,P<0. 01), prehension、Digit span、Vocabulary、Coding、pletion of test were reduced significantly in pared with those of control group(t=,,,,,P<0. 01); The prolonged latency of N2 were correlated significantly with the reduced scores prehension、Arithmetic、pletion in GAD, the prolonged latency of N2 were significantly correlated with the reduced scores prehension、Digit span、Codin