文档介绍：血浆同型半胱氨酸在缺血性脑血管疾病中的变化和意义
【摘要】目的探讨缺血性脑血管疾病患者血浆中同型半胱氨酸(homocystein, Hcy) 水平及临床意义。方法以健康体检者100例作为正常对照组,将153例缺血性脑血管疾病患者按疾病分2组,A组:84例椎基底动脉供血不足患者,依据是否伴有动脉粥样硬化再分A1组(椎基底动脉供血不足伴有动脉粥样硬化),A2组(椎基底动脉供血不足不伴有动脉粥样硬化);B组:69例脑血栓形成患者,依据是否伴有动脉粥样硬化再分为B1组(脑血栓形成组伴有动脉粥样硬化,B2组(脑血栓形成不伴有动脉粥样硬化),分析各组患者血清Hcy水平与缺血性脑血管疾病的关系。结果缺血性脑血管疾病患者各组血浆Hcy水平均高于对照组;A组中伴有动脉粥样硬化的患者(A1组)血清Hcy水平明显高于不伴有动脉粥样硬化患者(A2组),差异有统计学意义, P < ,在B组,尽管B1组患者血清Hcy水平均高于B2组,但差异无统计学意义, P>。结论血浆Hcy 水平的升高与缺血性脑血管疾病发生发展正相关,与动脉粥样硬化关系更密切。
【关键词】缺血性脑血管疾病脑血栓形成动脉粥样硬化同型半胱氨酸
【Abstract】 Objective To investigate the plasm homocysteine level in different patients with ischaemic cerebral vascular disease and its clinical significance. Methods: 100 cases healthy individuals were nocmal con
trols; 153 patients with ischaemic cerebral vascular disease were divided into 2 groups ,group A, 84 patients with vertebrovascular insufficiency cases according to vascular atherosclerosis, were divided into A1 (vertebrovascular insufficiency with vascular atherosclerosis )and A2 (vertebrovascular insufficiency without vascular atherosclerosis);Groups B ,69 patients with cerebralthrombosis according to vascular atherosclerosis were divided into B1(with vascular atherosclerosis)and B2 group(without vascular atherosclerosis) . And then the interrelation between the homocysteine levels, the disease and panying diseases were analyzed. Results: The plasm homocystein