文档介绍：TP方案与PF方案化疗治疗晚期食管癌的近期疗效对比分析
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[摘要] 目的探讨TP方案化疗与PF方案治疗晚期食管癌的近期疗效。方法回顾性分析2013年4月―2016年3月该院收治的晚期食管癌患者60例,分为TP组(n=36;紫杉醇135 mg/m2 d1;顺铂20 mg/m2 d1-3)与PF方案组(n=24;5-***尿嘧啶500 mg/m2泵持续推注 d1-5;顺铂 25 mg/m2 d1-3);观察两组患者的近期疗效及毒性反应。结果 %,明显比PF组高(%)(P<);%,%,两组患者间不良反应发生率组间差异无统计学意义(P>)。结论 TP(紫杉醇联合顺铂)方案化疗能提高晚期食管癌患者的近期疗效,同时其毒副反应发生率并未增高,可认为安全有效。
[关键词] TP方案;PF方案;晚期食管癌
[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2017)03(a)-0099-03
Comparative Analysis of Long-term Curative Effect of TP Plan and PF Plan Chemotherapy in Treatment of Esophageal Cancer
CHEN Qing, MA De
Department of Oncology, Jingjiang People’s Hospital, Jingjiang, Jiangsu Province, 214500 China
[Abstract] Objective To observe and analyze the long-term curative effect of TP plan and PF plan chemotherapy in treatment of esophageal cancer. Methods 60 cases of patients with esophageal cancer admitted and treated in our hospital from April 2013 to March 2016 were retrospectively analyzed, and divided into the TP group and PF group, the TP group (n= 36) adopted the taxinol of 135 mg/m2 d1 and cis-plexes of 20 mg/m2 d1-3, the PF group (n=24) adopted the 5-fluorouracil of 500 mg/m2 and cis-plexes of 25 mg/m2 d1-3, and the long-term curative effect and toxic reaction of the two groups were obser