文档介绍：瘢痕性天疱疮35例临床分析
(作者:___________单位: ___________邮编: ___________)
【摘要】目的:探讨瘢痕性天疱疮临床特点,为临床诊治提供帮助。方法:回顾性分析200201/200801我科诊治的35例瘢痕性天疱疮临床特点。结果:,男女性别比为20∶15,,%以口腔黏膜病变首发,%以眼部病变首发,眼睑内翻倒睫/慢性结膜炎和干眼/角膜病变为5/4/2,%以其它黏膜病变首发。经过治疗,%(25/35)患者症状消失或缓解超过3mo,%(5/35)患者症状反复或无明显缓解,%(5/35)患者中途退出治疗。%(13/35)患者出现全身其它异常,其中6例出现肝功能异常,2例终止治疗,肾功能异常2例,1例终止治疗,血液系统异常3例,1例退出治疗,心肌梗塞1例,退出治疗,明显血压升高1例。结论:瘢痕性天疱疮是一种慢性病,多发于老年人,男性稍多于女性,眼组织经常受累,多表现为干眼症、睑球粘连和内翻倒睫。瘢痕性天疱疮治疗复杂,经常需要多学科协作。
【关键词】瘢痕性天疱疮;睑球粘连;干眼症
RESULTS:The average age of ocular cicatricial pemphigoid was years, and the rate of male and female gender was 20/15. The average history was years. The oral mucosa was firstly invaded in % patients, ocular mucosa in % ones, and other mucosa in % ones. In eyeinvolved patients, the rate of eyelid entropium and trichiasis, dry eye and chronic conjunctivitis, and corneopathy was 5/4/2. After treatment, %(25/35) cases were cured, while % (5/35)cases were not cured, and %(5/35)cases did not plished the regimen. In the course of treatment, plications were found in % (13/35)cases, and among these, abnormal liver function was found in 6 cases and 2 cases withdrew from treatment, abnormal kidney function in 2 cases and 1 case discontinued the protocal, abnormal blood system in 3 cases and 1 case quitted the regimen, m