文档介绍：The exploration of mammalian mitochondrial genes
through integrating multiple lines of genome-wide
biological evidence
Jiabao Xu, Sunpeng Wang, Zhongrui Yi, Yizheng Quansheng Feng, Xinjian Fan*
Zhang, Xiao Li* Chengdu University of TCM
College of Life Sciences Chengdu, People’s Republic of China
Sichuan University fanxj531008@
Chengdu, People’s Republic of China
******@scu.
Abstract—Mitochondria are a anelle of eukaryotic cells. catalog of mitochondrial proteins and reduce the false
Many diseases are caused by the mitochondrial gene mutation , discovery, we predicted the mitochondrial genes by integrating
therefore, there is an urgent requirement to explore the proteins these 13 datasets with software weka and we obtained
of mitochondrion. In this paper we have created a list of 1086 1086 mitochondrial genes.
human mitochondrial genes bining 13 datasets from
publications or genomic experiments. Then we created a However, in the small number of known mitochondrial
functional work among mitochondrial genes by genes, some of them were not annotated specifically. To make
integrating multiple lines of biological evidence, and utilized the further progress, functions of the mitochondrial genes were
network to predict the function of the mitochondrial genes, predicted. So far, to understand the function of the
including identifying some